HYDROXYETHYLAMINO SULFONAMIDES OF HETEROCYCLOCARBONYL AMINO ACIDS, A PHARMACEUTICAL COMPOSITION, METHODS FOR INHIBITING RETROVIRAL PROTEASES AND PREVENTING RETROVIRAL REPLICATION, AND ALSO METHODS FOR TREATMENT OF A RETROVIRAL INFECTION

摘要

Selected heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide compounds of formula (I) are effective as retroviral protease inhibitors, and in particular as inhibitor of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and the treatment of a retroviral infection. (I)