mutants of shigella in the functions relating to the processes of maturation and recycling of peptidoglicani and their use as immunogeni.

摘要

Bacteria belonging to the Shigella genus, mutated to inactivate the function of at least one of the gene products responsible for the metabolism and/or recycling of the peptidoglycans of the cellular wall, for immunogenic use, especially mutated at SltY, MltA, MltB, ampG, amiA, MppA genes, and immunogenic compositions comprising them.