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SPRAYABLE BONE REPLACEMENT MATERIAL CONTAINING FIBRINE OR FIBRINOGEN AND HYDROXYLAPATITE CEMENT
SPRAYABLE BONE REPLACEMENT MATERIAL CONTAINING FIBRINE OR FIBRINOGEN AND HYDROXYLAPATITE CEMENT
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机译:包含纤维蛋白或纤维蛋白原和羟基磷灰石水泥的可喷射骨置换材料
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摘要
A bone substitute material is prepared which comprises a soft matrix, living cells and a setting matrix comprising non-ceramic hydroxyapatite cement. The bone substitute material can be injected minimally invasively into a bone defect with a suitable injection apparatus. In an embodiment, living cells are mixed with a fibrinogen solution and then with a thrombin solution to form the soft matrix, and the soft matrix is mixed with an aqueous solution of non-ceramic hydroxyapatite cement to obtain the bone substitute material which remains unsolidified until after application to a body.
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