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method for removing systematic errors and deviations and to estimate random errors in chemical and biological testing
method for removing systematic errors and deviations and to estimate random errors in chemical and biological testing
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机译:化学和生物学测试中消除系统误差和偏差并估计随机误差的方法
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摘要
A method for improving the reliability and/or accuracy of physical measurements obtained from array hybridization studies performed on an array having a large number of genomic samples uses a small number of replicates insufficient for making precise and valid statistical inferences. This is overcome by estimating an error in measurement of a sample by averaging errors obtained when measuring the large number of samples or a subset of the large number of samples. The estimated sample error is utilized as a standard for accepting or rejecting the measurement of the respective sample. The samples may be independent or dependent in that correlated across two or more conditions.
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