Procollagen aminoterminal propeptide of type 1, the antibody and analysis method using the same.

摘要

THE aminoterminal propeptide procollagen TYPE I MEXISTE IN SERUM OF TWO WAYS: procollagen conventional type I WHICH IS A heterotrimer containing two STRINGS PRO {AL} 1 AND CHAIN ​​PRO {AL} 2 procollagen type I AND procollagen {AL } 1HOMOTRIMERO TYPE I CONTAINING THREE CHAINS PRO {1} IDENTICAL TO. THESE trimeric aminoterminal propeptides Principled can be isolated without the use of proteolytic enzymes and the resulting propeptides may be used to prepare antibodies specific for ENTIRETY trimeric propeptide, having affinity for monomeric form of the propeptide. Such antibodies are useful in assay methods trimeric aminoterminal propeptide procollagen ENTIRETY TYPE I IN SERUM WITHOUT Misinformation RESULTING FROM THE TRIALS inadvertent monomeric form of the propeptide.