CRYSTALLINE FORMS OF ENDO-2,3-DIHYDRO-N-(8-METHYL-8-AZABICYCLO-3.2.1.OCT-3-YL)-2-OXO-1H-BENZIMIDAZOLE-1-CARBOXAMIDE HYDROCHLORIDE MONOHYDRATE AND OF ENDO-3 ETHYL-2,3-DIHYDRO-N-(8-METHYL-8-AZABICYCLO3.2.1.OCT-3-YL)-2-OXO-1H-BENZIMIDAZOLE-1-CARBOXAMIDE HYDROCHLORIDE MONOHYDRATE

摘要

Crystalline monohydrates of endo-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo -1H-benzimida-zole-1-carboxamide hydrochloride and of endo-3-ethyl-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1H-benzimidazole-1-carboxamide hydrochloride offormula(See formula I)(Compound 2a: R = H](Compound 2b: R - C2H5)the processes for their preparation and pharmaceuticalcompositions containing them.