INHIBITION OF RESPIRATORY BURST USING POSTTRANSLATIONAL MODIFICATION INHIBITORS

摘要

The present invention relates to the use of posttranslational modificationinhibitors, such as isoprenylation inhibitors, toinhibit activation of phagocyte NADPH oxidase and respiratory burst.Therapeutic medicaments and compositions containingvarious inhibitors, and methods of making and using same, are also disclosed.