A NOVEL PROCESS FOR PREPARING INTERMEDIATES OR INHIBITORS OF ENKEPHALINASE AND ANGIOTENSIN CONVERTING ENZYME AND INTERMEDIATES THEREOF

摘要

The present invention relates to a novel process forpreparing intermediates of formula (I) and to novelintermediates thereof which are useful in the preparationof inhibitors of enkephalinase and angiotensin convertingenzyme.(See formula I)whereinG completes an aromatic ring selected from the groupconsisting ofwhereinX1 is selected from the group consisting of S and NH;X2 is selected from the group consisting of 5, 0, andNH; andR is selected from the group consisting of hydrogen,hydroxy, phenyl, and C1-C4 alkoxy.