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ANTHRANYL DERIVATIVES HAVING AN ANTICHOLECYSTOKININ ACTIVITY(ANTI-CCK-1), A PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL USE THEREOF
ANTHRANYL DERIVATIVES HAVING AN ANTICHOLECYSTOKININ ACTIVITY(ANTI-CCK-1), A PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL USE THEREOF
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机译:具有抗胆囊收缩素活性(ANTI-CCK-1)的蒽基衍生物及其制备方法和其医药用途
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摘要
Anthranylic compounds having anti-CCK activity of general formula (I) in which, n is a whole number lying between 0 and 7; R1 is chosen independently from the groups (II), in which X1 is chosen independently from, S, O, NR2 an d X2 is a group chosen from: H, C1-C4 alkyl, F, Cl, CF3, OCH3, OC2H5, CN; R2 i s chosen from H or CH3; R3 is chosen from H, CH3, F, Cl, CF3, OCH3; R4 is chos en from the groups: H, -S-(CH2)m-R5, -SO2- (CH2)m-R5 (n different from 0), a branched alkyl group, a cyclo alkyl, a cyclo alkenyl, the group 1 or 2 adamantile, a phenyl group optionally substituted; R5 is chosen from the groups: H, linear or branched alkyl, cyclo alkyl, the group 1 or 2 adamantil e, a suitably substituted phenyl group.
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