METHOD AND SYSTEM FOR INVESTIGATION OF CENTRAL NERVOUS SYSTEM DRUGS USING 3-D BRAIN SOURCE LOCALIZATION

摘要

A method for determining effects of a drug on a central nervous system (CNS)of a subject, comprises the steps of: detecting and locating three-dimensional(3-D) brain source regions of first brain waves of the subject using afunctional neuroimaging system, the first brain waves being indicative of aCNS disorder and comparing the first brain waves at each of the regions tocontrol data corresponding to brain wave activity of corresponding brainregions in the absence of the CNS disorder. After these steps the drug isadministered to the subject and second brain waves of the subject are measuredfrom the brain source regions and compared to one of the first brain waves andthe control data. The drug's effectiveness in regard to the CNS disorder isthen determined based on the comparison.