A METHOD FOR THE TREATMENT, PREVENTION, OR INHIBITION OF A CNS DISORDER AND/OR PAIN AND INFLAMMATION USING A COMBINATION OF DULOXETINE, VENLAFAXINE OR ATOMOXETINE AND A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND COMPOSITIONS THEREOF

摘要

A method of treating, preventing, or inhibiting a CNS disorder and/or pain andinflammation or an inflammation-associated disorder in a subject in need ofsuch treatment or prevention provides for treating the subject withduloxetine, venlafaxine or atomoxetine and a cyclooxygenase-2 selectiveinhibitor or prodrug thereof, wherein the amount of duloxetine, venlafaxine oratomoxetine and the amount of a cyclooxygenase-2 selective inhibitor orprodrug thereof together constitute a CNS disorder, pain and inflammation, orinflammation-associated disorder suppressing treatment, prevention, orinhibition effective amount of the composition. Compositions andpharmaceutical compositions that contain duloxetine, venlafaxine oratomoxetine and a cyclooxygenase-2 selective inhibitor are also disclosed.