ANTISENSE MODULATION OF BETA-SITE APP-CLEAVING ENZYME EXPRESSION

摘要

Antisense compounds, compositions and methods are provided for modulating the expression of beta-site APP-cleaving enzyme. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding beta-site APP-cleaving enzyme. Methods of using these compounds for modulation of beta-site APP-cleaving enzyme expression and for treatment of diseases associated with expression of beta-site APP-cleaving enzyme are provided.