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METHODS FOR ESTIMATING HAPLOTYPE FREQUENCIES AND DISEASE ASSOCIATIONS WITH HAPLOTYPES AND ENVIRONMENTAL VARIABLES
METHODS FOR ESTIMATING HAPLOTYPE FREQUENCIES AND DISEASE ASSOCIATIONS WITH HAPLOTYPES AND ENVIRONMENTAL VARIABLES
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机译:估计个体型和环境变量的个体型频率和疾病关联的方法。
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摘要
The invention provides methods for estimating haplotype frequencies using an estimating equation method and a forward-block algorithm that provides a standard error measurement for each estimated haplotype frequency. The methods may be used, for example, for estimating a set of haplotype frequencies in a population, for assessing the association of a haplotype with a trait, and for assessing the association of haplotypes for one or more set of markers and one or more environmental factors with a trait. The invention also provides a computer-readable medium having computer-readable instructions for performing the methods of the invention, and a computer-system for performing the methods of the invention.
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