S-SUBSTITUTED N-1-((HETERO)ARYL)ALKYL-N2-((HETERO)ARYL) ALKYLYSOTHIOCARBAMIDES, METHOD FOR THE PRODUCTION THEREOF, PHYSIOLOGICALLY ACTIVE S-SUBSTITUTED N-1-((HETERO)ARYL)ALKYL-N2-((HETERO)ARYL)ALKYLYSOTHIOCARBAMIDES, A PHARMACEUTICAL COMPOUND AND CURING METHOD

摘要

The invention relates to s-substituted N-1-[(hetero)aryl]alkyl-N'-1-[(hetero)aryl] alkylysothiocarbamides and the physiologically active salts and bases thereof, embodied in the form of racemic mixtures (or stereoisomer mixture) or individual optical isomers. The specific physiological activity of said compounds makes it possible to use them in the form of molecular tools . Said invention also relates to Pharmaceutical compositions, containing said compounds and to a method for preventing and curing various diseases including neurodegenerative diseases as, for example Alzheimer's disease (AD). The pharmacological effect of said compounds is based on the combined cognitive-stimulating and neuroprotective action thereof, which is produced by acting on chemo-controlled calcium channels of neurone membranes, in particular the neurones regulated by glutamate receptors of the central neural system (CNS).