首页> 外国专利> Copper agonist that binds on the copper binding site of APP and/or exerts an inhibiting effect on the release of amyloid A beta peptide

Copper agonist that binds on the copper binding site of APP and/or exerts an inhibiting effect on the release of amyloid A beta peptide

机译:与APP的铜结合位点结合和/或对淀粉样蛋白Aβ肽释放具有抑制作用的铜激动剂

摘要

The invention relates to copper agonists that bind on the copper binding site of APP and/or exert an inhibiting effect on the release of the amyloid Abeta peptide participating in the emergence of Alzheimer's disease. The invention also relates to the drugs containing said copper agonists or to the utilization of said copper agonists for the preparation of a drug for the prevention and/or treatment of Alzheimer's disease. The invention further relates to a method for identifying copper agonists having the desired effect described in the invention.
机译:本发明涉及结合在APP的铜结合位点上和/或对参与阿尔茨海默氏病出现的淀粉样蛋白Aβ肽的释放起抑制作用的铜激动剂。本发明还涉及含有所述铜激动剂的药物或所述铜激动剂在制备用于预防和/或治疗阿尔茨海默氏病的药物中的用途。本发明进一步涉及一种鉴定具有本发明中描述的期望效果的铜激动剂的方法。

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