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New indolocarbazole alkaloids from a marine actinomycete
New indolocarbazole alkaloids from a marine actinomycete
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机译:海洋放线菌的新吲哚并咔唑生物碱
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摘要
The invention provides compounds of formula (1) wherein R1 is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; and R2 is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; and pharmaceutically acceptable salts thereof. The invention also relates to a process for obtaining the compounds, compositions containing them and their therapeutic use. The compounds display excellent activity against mammalian cancer cell lines.
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机译:本发明提供了式(1)的化合物,其中R 1是氢原子,具有1-6个碳原子的烷基或具有1-6个碳原子的烷氧基; R 2为氢原子,碳原子数1〜6的烷基或碳原子数1〜6的烷氧基。及其药学上可接受的盐。本发明还涉及获得化合物,包含它们的组合物及其治疗用途的方法。该化合物对哺乳动物癌细胞系显示出优异的活性。
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