Oxalatoplatin and 5-fluorouracil for combination therapy of cancer

摘要

For a combination of a first carcinostatic agent comprising cis-oxalato (1R, 2R-diaminocyclohexane)Pt(II) and of a second carcinostatic agent consisting of 5-fluorouracil in manufacturing a medicament for the treatment of cancer in a patient, it has been found that by separately administrating a synergistically effective amount of a first carcinostatic agent followed by administration of a synergistically effective amount of a second carcinostatic agent, a sensibly enhanced effectiveness is observed.;Preferably, a synergistically effective amount of cis-oxalato (1R, 2R-diaminocyclohexane)Pt(II) alone or in combination with another agent, is administered before or after having administered a synergistically effective amount of 5-fluorouracil.