USE OF L-CARNITINE AND DERIVATIVES FOR REDUCING CERAMIDE LEVELS AND POTENTIATING ANTIRETROVIRAL

摘要

PCT No. PCT/IT96/00146 Sec. 371 Date Feb. 3, 1998 Sec. 102(e) Date Feb. 3, 1998 PCT Filed Jul. 19, 1996 PCT Pub. No. WO97/05864 PCT Pub. Date Feb. 20, 1997The present invention provides a novel use of L-carnitine, the derivatives thereof and their pharmacologically acceptable salts in combination with antiretroviral drugs for reducing ceramide levels and enhance the activity of the aforesaid antiretroviral drugs for the therapeutic treatment of HIV-infection and AIDS.