The radiology instrument comprises a source (Trx) emitting X-radiation, a radiological image receiver (II, CV), a chassis (CS) arranged between the X-ray source and the image receiver in order to accommodate an object (TT) to be radiographed, and a positioning and guiding device which can be connected to the chassis and can intercept the X-radiation so as to position and guide probes intended to interact with the object. The positioning and guiding device has first means (CS, Rg, GC2) forming a retractable guide grid having holes whose respective axes converge towards the focal point (F) of the source when the first means intercept the conical radiation, and a retractable positioning grid (Gr) with holes.
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