METHOD OF QUANTITATIVE DETERMINATION OF CARDIAC MUSCLE CONTRACTION BY ELECTROCARDIOGRAM-SYNCHRONIZED TRANSVERSE TOMOGRAM

摘要

From ECG-gated SPECT or PET images of radioactive myocardial perfusion imaging agents, contraction of the myocardium along the tangential direction, i.e., in the direction parallel to the myocardium, can be evaluated. The amount of the agents which accumulate in the heart muscle is calculated from reconstructed short-axis ECG-gated images and is projected on a virtual cylindrical screen whose axis is the same as the long axis of the heart. Spatial and temporal changes in time and space in the projected count distribution on the screen are described by a two-dimensional second order differential equation, which is called an equation of continuity for the fluid. This equation can be solved numerically with a computer. The displacements of points on the myocardium in the tangential direction are calculated by projecting the displacement of each point back onto the cardiac wall. From these displacements, contraction and expansion of the heart muscle can be quantified.