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PROCESS FOR THE SYNTHESIS OF ISONICOTINIC ACID HYDRAZIDE

机译：异烟酰胺酸酰肼的合成方法

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摘要

The invention provides a process for the manufacture of isonicotinic acid hydrazide (INH) useful in the treatment of tuberculosis. The invention relates to the single step conversion of isonicotinamide by hydrazine hydrate to isonicotinic acid hydrazide (INH) of yield greater than 95 % (w/w) and purity more than 99 %.

机译：本发明提供了用于治疗肺结核的异烟酸酰肼（INH）的制备方法。本发明涉及通过水合肼将异烟酰胺单步转化为产率大于95％（w / w）且纯度大于99％的异烟酸酰肼（INH）。

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公开/公告号WO2004056778A1

专利类型
公开/公告日2004-07-08

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申请/专利权人 COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH;YADAV SATYA NIKETAN;BANDYOPADHYAY ANUP KUMAR;RAY SUBHASH CHANDRA;NANDI LAKSHMI NARAYAN;SINGH BALDEV;PRASAD HIRALAL;MAHARAJ SUMANT;SARKAR PRODYOT KUMAR;DUTTA PASHUPATI;ROY SHYAM KISHORE;
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申请/专利号WO2002IB05605
发明设计人 SINGH BALDEV;PRASAD HIRALAL;SARKAR PRODYOT KUMAR;DUTTA PASHUPATI;NANDI LAKSHMI NARAYAN;RAY SUBHASH CHANDRA;MAHARAJ SUMANT;YADAV SATYA NIKETAN;BANDYOPADHYAY ANUP KUMAR;ROY SHYAM KISHORE;
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申请日2002-12-23
分类号C07D213/86;C07B43/06;
国家 WO
入库时间 2022-08-21 22:55:34

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