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COMPOUND LIBRARIES OF 1,3,5-SUBSTITUTE INDAZOLE DERIVATIVES AS COMPOUNDS FOR TARGETTING COMPOUNDS CAPABLE OF BINDING TO THE G-PROTEIN COUPLED RECEPTOR
COMPOUND LIBRARIES OF 1,3,5-SUBSTITUTE INDAZOLE DERIVATIVES AS COMPOUNDS FOR TARGETTING COMPOUNDS CAPABLE OF BINDING TO THE G-PROTEIN COUPLED RECEPTOR
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机译:1,3,5-取代的吲哚衍生物的化合物库,作为靶向可与G蛋白偶联受体结合的化合物的化合物
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摘要
The present invention provides a compound library that is targeted against a group of peptide liganded receptors, which can be characterised broadly as requiring an interaction with an amide or acid function interacting largely by hydrogen bonding. In addition the library picks up interactions for electron-rich aromatic rings and other interactions. The library comprises or consists of a set of structurally related compounds of general formulae (A), (B) and (C), as well as intermediates of structure (I).
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