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INTERSTRAND CROSSLINKING AGENTS FOR DNA AND COMPOUNDS THEREFOR
INTERSTRAND CROSSLINKING AGENTS FOR DNA AND COMPOUNDS THEREFOR
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机译:链间交联剂及其相关化合物
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摘要
Compounds represented by the general formula (I): which two DNA strands can be interstrand-crossliked: A-L-B-X-B-L-A wherein B represents a chemical structure capable of recognizing the nucleotide sequence of DNA; A represents a chemical structure capable of binding to one of the bases of DNA; L represents a linker by which the chemical structures of A and B can be linked to each other; X represents a spacer by which the A-L-B components can be linked to each other. A method of interstrand-crosslinking DNA by using these compounds; and medicinal compositions containing interstarand-crosslinking agents of DNA. IMAGE
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