METAL ION ASSISTED N- N-(3,3-DIMETHYLBUTYL)-L-ALPHA-ASPARTYL-L-PHENYLALANINE 1-METHYL ESTER ISOMER RESOLUTION

摘要

This invention relates to the purification of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester by resolving a mixture of the alpha- and beta-isomers of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester using metal ions.