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DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH DOPAMINE RECEPTOR D5 (DRD5)
DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH DOPAMINE RECEPTOR D5 (DRD5)
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机译:多巴胺受体D5(DRD5)相关疾病的诊断和治疗
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摘要
The invention provides a human DRD5 which is associated with the cardiovascular disorders, metabolic diseases, gastrointestinal and liver diseases, cancer disorders, inflammatory diseases, hematological disorders, neurological disorders, respiratory diseases and urological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, metabolic diseases, gastrointestinal and liver diseases, cancer disorders, inflammatory diseases, hematological disorders, neurological disorders, respiratory diseases and urological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of DRD5 as well as pharmaceutical compositions comprising such compounds.
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