A METHOD TO INCREASE EXPRESSION OF PGD2 RECEPTORS AND ASSAYS FOR IDENTIFYING MODULATORS OF PROSTAGLANDIN D2 RECEPTORS

摘要

The present invention provides cell lines expressing endogenous PGD2-specific receptors, methods for increasing expression of the receptors and assays utilizing the hereindisclosed cell lines for identifying modulators of the PGD2-specific receptors. Increasing expression of PGD2-specific receptors is achieved by treating the disclosed cell lines with an agent that induces differentiation.