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PLATINUM(II)- AND PLATINUM(IV)-COMPLEXES AND THEIR USE

机译:铂(II)和铂(IV)复合物及其用途

摘要

Platinum(II) complexes are provided selected from the group consisting of compounds of the general formulae I to IV and physiologically acceptable addition salts thereof, wherein the radicals R1 to R4, R1' to R3', X, X', Y, a, i, k and n are defined as in the description, and mixtures of the compounds for use as prophylactic and/or therapeutic agents for the treatment of diseases, and cytostatic platinum complexes with the general formulae [PtII(NH3)n(A)n(Z)2-n] or [PtIV(NH3)n(A)n(Z)2-nX2]and [PtII(A)1(Z)2] or [PtIV(A)1(Z)2X2] wherein A, Z and n are as defined in the description.
机译:提供选自通式I至IV的化合物及其生理学上可接受的加成盐的铂(II)配合物,其中基团R 1至R 4,R 1'至R 3 '>,X,X',Y,a,i,k和n如说明书中所定义,以及用作疾病预防和/或治疗剂的化合物的混合物,以及具有通式[Pt II,(NH3)n(A)n(Z)2-n]或[PtIV(NH3)n(A)n(Z)2-nX2]和[PtII( A)1(Z)2]或[Pt IV(A)1(Z)2X2],其中A,Z和n如说明书中所定义。

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