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Transdermal preparations comprising eperisone tolperisone or salts thereof

机译:包含依哌立酮托哌酮或其盐的透皮制剂

摘要

PURPOSE: Provided is a transdermal preparation comprising eperisone, tolperisone or salts thereof to maximize the absorption of eperisone, tolperisone or salts thereof into the skin, and increase the stability thereof or skin adhesion. CONSTITUTION: A transdermal preparation is characterized by containing a mixture of a drug selected from eperisone, tolperisone or salts thereof, an acrylate adhesion agent having a hydroxy functional group and an acrylate adhesion agent having no hydroxy functional group. The content of the drug is 5-20 wt.%, salts are hydrochlorides or phosphates, and the mixing ratio of the acrylate adhesion agent having a hydroxy functional group to the acrylate adhesion agent having no hydroxy functional group is 8:2 to 5:5.
机译:目的:提供一种透皮制剂,其包含艾培瑞松,托哌酮或其盐,以使艾培瑞松,托哌酮或其盐在皮肤中的吸收最大化,并增加其稳定性或皮肤粘附性。组成:一种透皮制剂,其特征在于,所述药物包含选自依匹松,托皮松或其盐的药物,具有羟基官能团的丙烯酸酯类粘附剂和不具有羟基官能团的丙烯酸酯类粘附剂的混合物。药物的含量是5-20wt。%,盐是盐酸盐或磷酸盐,并且具有羟基官能团的丙烯酸酯粘合剂与不具有羟基官能团的丙烯酸酯粘合剂的混合比是8:2至5: 5,

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