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Transdermal preparations comprising eperisone tolperisone or salts thereof
Transdermal preparations comprising eperisone tolperisone or salts thereof
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机译:包含依哌立酮托哌酮或其盐的透皮制剂
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摘要
PURPOSE: Provided is a transdermal preparation comprising eperisone, tolperisone or salts thereof to maximize the absorption of eperisone, tolperisone or salts thereof into the skin, and increase the stability thereof or skin adhesion. CONSTITUTION: A transdermal preparation is characterized by containing a mixture of a drug selected from eperisone, tolperisone or salts thereof, an acrylate adhesion agent having a hydroxy functional group and an acrylate adhesion agent having no hydroxy functional group. The content of the drug is 5-20 wt.%, salts are hydrochlorides or phosphates, and the mixing ratio of the acrylate adhesion agent having a hydroxy functional group to the acrylate adhesion agent having no hydroxy functional group is 8:2 to 5:5.
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