MEDICAL BIODEGRADABLE SYNTHETIC POLYMER COMPRISING REACTION PRODUCT OF ALPHA, BETA-UNSATURATED POLYBASIC ACID OR DERIVATIVE THEREOF, MONOGLYCERIDE AND FUNCTIONALIZING AGENT, COMPOSITION CONTAINING THE POLYMER AND MEDICAL APPARATUS CONTAINING COATED PRODUCT CONTAINING THE POLYMER

摘要

PURPOSE: Provided are a biodegradable synthetic polymer for medical or pharmaceutical use, a composition containing the polymer and a medical apparatus containing a coated product containing the polymer. CONSTITUTION: The synthetic polymer comprises a reaction product of an ,-unsaturated polybasic acid or its derivative, a monoglyceride, and a functionalizing agent comprising a first functional nucleophilic residue and a second functional nucleophilic residue other than the first functional nucleophilic residue pended in a polymer. Preferably the ,-unsaturated polybasic acid or its derivative is selected from the group consisting of maleic acid, fumaric acid, citraconic acid, itaconic acid, maleic anhydride, mixture anhydride, an ester, an activated ester and an acid halide; and the monoglyceride is selected from the group consisting of monostearoyl glycerol, monopalmitoyl glycerol, monomyristoyl glycerol, monocaproyl glycerol, monodecanoyl glycerol, monolauroyl glycerol, monolinoleoyl glycerol and monooleoyl glycerol.