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METHOD FOR PREPARING NON-STEROID MODULATING AGENT OF GLUCOCORTICOID RECEPTORS AND INTERMEDIATE COMPOUNDS
METHOD FOR PREPARING NON-STEROID MODULATING AGENT OF GLUCOCORTICOID RECEPTORS AND INTERMEDIATE COMPOUNDS
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机译:糖皮质激素受体和中间化合物的非类固醇调节剂的制备方法
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摘要
FIELD: organic chemistry, hormones. SUBSTANCE: invention relates to method for preparing compound of the formula (I): from carboxylic acid and amine in the presence of 1,1'- carbonyldiimidazole using new intermediate compounds and new intermediate compounds also. Invention provides preparing compound useful as non-steroid modulating agent of glucocorticoid receptors. EFFECT: improved preparing method, valuable properties of agent. 16 cl, 9 ex
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机译:领域:有机化学,激素。物质:本发明涉及制备式(I)化合物的方法:<图像文件=“ 00000002.GIF” he =“ 51” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 63” />由羧酸在1,1'-羰基二咪唑存在下,使用新的中间体化合物和新的中间体化合物制备胺和胺。本发明提供了用作糖皮质激素受体的非类固醇调节剂的制备化合物。效果:改进的制备方法,试剂的宝贵性能。 16 cl,9前
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