STRAIN OF SUSPENSION CULTURE OF VEGETABLE CELLS NICOTIANA TABACUM (SV, SAMSUN) AS PRODUCER OF RECOMBINANT ANTIBODIES TO HUMAN SPLEEN FERRITIN

摘要

FIELD: immunobiotechnology, protein engineering. SUBSTANCE: invention can be used for preparing monoclonal antibodies. The strain Nicotiana tabacum (sv. Samsun) F11B016 is deposited an number VKKK = 65 and represents rapidly growing and productive suspension culture of cells from leaf explants of transgenic plants Nicotiana tabacum. The strain F11B016 is able to grow in bioreactor and to synthesize antibodies to human spleen ferritin, it synthesizes the full-scale gene only and doesn't form hydrolytic product. Invention enhances technological effectiveness in preparing antibodies and provides ecological safety of process. EFFECT: improved preparing method, valuable medicinal properties of antibodies. 2 tbl