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MIMETIC OF BETA LEAFLET AND METHOD FOR USE THEREOF

机译:BETA传单的隐喻及其使用方法

摘要

beta -sheet mimetics and methods relating to the same are disclosed. The beta -sheet mimetics have utility as protease and kinase inhibitors, as well as inhibitors of transcription factors and protein-protein binding interactions. Methods of the invention include administration of a beta -sheet mimetic, or use of the same for the manufacture of a medicament for treatment of a variety of conditions associated with the targeted protease, kinase, transcription factor and/or protein-protein binding interaction.
机译:公开了一种β-折叠模拟物及其相关方法。 β-折叠模拟物可用作蛋白酶和激酶抑制剂,以及转录因子和蛋白质-蛋白质结合相互作用的抑制剂。本发明的方法包括给予β-片层模拟物,或将其用于制备用于治疗与靶标蛋白酶,激酶,转录因子和/或蛋白质-蛋白质结合相互作用有关的多种病症的药物。

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