PROTEIN RETREATMENT PROCEDURES FOR THE USE OF WESTERN ACTIVITIES OF THE NETHERLANDS MOLECULAR WEIGHT

摘要

Methods are disclosed for refolding proteins of the TGF-beta family of proteins. The methods employ as refolding agents one or more compounds which are non-detergent zwitterionic compounds, such as sulfobetaines, substituted pyridines, substituted pyrroles and acid substituted aminocyclohexanes.