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CHEMISCHE SYNTHESE VON 6-O-ALKYL ERYTHROMYCIN A
CHEMISCHE SYNTHESE VON 6-O-ALKYL ERYTHROMYCIN A
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机译:化学合成6-邻烷基红霉素A
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摘要
A process of preparing 6-O-alkyl erythromycin A is provided. The process includes the steps of protecting the oxime hydroxyl of 9-oxime erythromycin A with a benzoyl protecting group, protecting the 2'-hydroxyl group and optionally the 4'-hydroxyl group with an O-protecting group, alkylating the 6-hydroxyl, removing the benzoyl and O-protecting groups and deoximating the 9-oxime.
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