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IN-VITRO STIMULATION OF BETA CELL REPRODUCTION

机译:贝塔细胞繁殖的体外刺激

摘要

The present invention relates to a method for increasing the number and/or the size of beta cells, for stimulating beta cell proliferation and for preventing diabetes. The invention is based on the recognition that GLP-1 acts as a beta cell growth factor. The invention also relates to a method for preventing or curing Type I or Type II diabetes, a method for obtaining a less severe disease stage in a subject suffering from Type II diabetes as well as methods of delaying the progression of impaired glucose tolerance (IGT) or non-insulin requiring Type II diabetes to insulin requiring Type II diabetes. The invention also relates to a cure for diabetes.
机译:本发明涉及增加β细胞的数量和/或大小,刺激β细胞增殖和预防糖尿病的方法。本发明基于对GLP-1充当β细胞生长因子的认识。本发明还涉及预防或治愈I型或II型糖尿病的方法,在患有II型糖尿病的受试者中获得不太严重的疾病阶段的方法以及延迟糖耐量减低(IGT)进展的方法。或需要II型糖尿病的非胰岛素到需要II型糖尿病的胰岛素。本发明还涉及糖尿病的治疗方法。

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