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NEW PROTEIN FAMILIES, NAMED ATIP, NUCLEIC SEQUENCES ENCODING SAID PROTEINS AND THEIR APPLICATIONS

机译:新蛋白家族,命名为ATIP,编码所述蛋白的核酸序列及其应用

摘要

The invention concerns a novel family of human proteins (hATIP) interacting with the angiotensin II receptor and having an antioncogenic function. Said family of proteins is therefore useful for diagnosing cancer and pre-cancer conditions and for treating cancer conditions. The invention also concerns the gene coding for said proteins, fragments of said gene and the uses thereof for detecting and expressing said proteins. The invention further concerns antibodies directed against said proteins and methods for detecting and/or screening pre-cancer or cancer condition using said proteins, said antibodies and/or various nucleic acid sequences.
机译:本发明涉及与血管紧张素II受体相互作用并具有抗癌作用的新型人蛋白质家族(hATIP)。因此,所述蛋白质家族可用于诊断癌症和癌前状况以及用于治疗癌症状况。本发明还涉及编码所述蛋白质的基因,所述基因的片段及其在检测和表达所述蛋白质中的用途。本发明进一步涉及针对所述蛋白质的抗体以及使用所述蛋白质,所述抗体和/或多种核酸序列检测和/或筛选癌前或癌症状况的方法。

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