首页> 外国专利> New 4-(dihydro-cyclopropa(a)inden-6a-yl)-1H-imidazole derivatives, useful as alpha-2 adrenergic receptor ligands for treating Alzheimer's disease or Parkinson's disease

New 4-(dihydro-cyclopropa(a)inden-6a-yl)-1H-imidazole derivatives, useful as alpha-2 adrenergic receptor ligands for treating Alzheimer's disease or Parkinson's disease

机译:新的4-(二氢-环丙烷(a)茚满-6a-基)-1H-咪唑衍生物,可用作治疗阿尔茨海默氏病或​​帕金森氏病的α-2肾上腺素能受体配体

摘要

4-(6-Spiro-1'-cyclopropane-1a,6-dihydro-1H-cyclopropa(a)inden-6a-yl)-1H-imidazoles (I), and their optionally hydrated mineral or organic acid addition salts, isomers (specifically the D- and L-isomers) and tautomers, are new. 4-(6-Spiro-1'-cyclopropane-1a,6-dihydro-1H-cyclopropa(a)inden-6a-yl)-1H-imidazoles of formula (I), and their optionally hydrated mineral or organic acid addition salts, isomers (specifically the D- and L-isomers) and tautomers, are new: R1 = H, F or OMe; R2 = H or Me; and R3 = H, Me or Et. An Independent claim is also included for the preparation of (I).
机译:4-(6-螺-1'-环丙烷-1a,6-二氢-1H-环丙烷(a)茚满-6a-基)-1H-咪唑(I)及其任选的水合矿物或有机酸加成盐,异构体(特别是D和L异构体)和互变异构体是新的。式(I)的4-(6-螺-1'-环丙烷-1a,6-二氢-1H-环丙烷(a)茚满-6a-基)-1H-咪唑及其任选的水合无机或有机酸加成盐,异构体(特别是D和L异构体)和互变异构体是新的:R1 = H,F或OMe; R2 = H或Me;并且R3 = H,Me或Et。独立索赔也包括在准备(I)中。

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