OSTEOCLAST DIFFERENTIATION INHIBITOR AND DRUG FOR OSTEOPOROSIS COMPRISING THE SAME

摘要

PROBLEM TO BE SOLVED: To obtain a compound minimizing differentiation from a hematopoietic stem cell contained in a bone marrow into an osteoclast and thereby affording osteogenesis superiority and carrying out prophylaxis or treatment of bone metabolic diseases such as osteoporosis.;SOLUTION: The osteoclast differentiation inhibitor is characterized as comprising a compound represented by formula (I) [wherein, R¹ is methyl group or ethyl group; R² is hydrogen atom or a 1-5C straight-chain or side-chain alkyl group; and R¹ and R² may each be the same or different] or its salt.;COPYRIGHT: (C)2006,JPO&NCIPI