APPARATUS AND METHOD FOR ESTIMATING INTERACTION OF GENE EXPRESSION, COMPUTER-READABLE RECORDING MEDIUM FOR RECORDING PROGRAM, AND PROGRAM

摘要

PPROBLEM TO BE SOLVED: To estimate many genes more quickly with smaller computer resources, relating to an apparatus and a method for estimating the interaction of gene expression to determine a gene network that represents interaction between genes. PSOLUTION: A degradation system coefficient estimating part 4 uses data on the time course of a disruption strain, and using the least-squares method calculates the optimal values of the degradation-system coefficients SBi/SB, hSBij/SBof an S-system model by using values converted into the logarithmic space of the data and a differential coefficient obtained from interpolation data. With the degradation system as a premise, a degradation system coefficient estimating part 5 uses data on the time course of non-disruptive strain data, calculates a generation-speed profile on the basis of values converted into the logarithmic space of the data and the interpolation data, and with the profile calculates the optimal values of generation-system coefficients SBi/SB, gSBij/SBusing the least-squares method. PCOPYRIGHT: (C)2006,JPO&NCIPI