METHOD AND APPARATUS FOR CUTANEOUS ABSORPTION ENHANCEMENT AND PERCUTANEOUS DRUG DELIVERY

摘要

PPROBLEM TO BE SOLVED: To provide an apparatus and a method for cutaneous absorption enhancement of drugs by applying electrical pulses. PSOLUTION: A treatment method and apparatus for providing a substance to be absorbed onto a surface of a patient's skin, includes applying the substance onto the surface of the patient's skin by way of a probe head that provides, at the same time: (i) bursts of electrical pulses to the skin surface, and (ii) vibrations to the skin surface. The vibrations are applied to the skin surface at a substantially same frequency rate, a first harmonic of the same frequency rate, and/or a second harmonic of the same frequency rate, as a burst rate of electrical pulses being applied to the skin surface. PCOPYRIGHT: (C)2006,JPO&NCIPI