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APPROXIMATION CORRECTION METHOD OF MEASUREMENT VALUE TO TOXIC EQUIVALENT USING BIOLOGICAL REACTION OF TOXIC CHEMICAL SUBSTRANCE

机译:毒性化学物质生物反应的毒性当量测量值近似校正方法

摘要

PROBLEM TO BE SOLVED: To provide an approximation correction method capable of calculating a corrected toxic equivalent approximated to a toxic equivalent of the world health organization from a value obtained by an easy and rapid measurement method that is a measurement method using a biological reaction such as immunoassay or bioassey.;SOLUTION: For a measurement value by this measurement method, on condition that the total quantity of the bonding amount of each compound contained in a toxic chemical substance such as dioxin with a ligand based on a respective specified reaction coefficient is quantitatively determined, and that the concentration composition ratio of each compound is substantially constant within a section with a common generating source of chemical substances, the estimated concentration of each compound is calculated by use of the preliminarily acquired concentration composition ratio of each compound, the estimated concentration is multiplied by a toxic equivalent factor of the world health organization to calculate an integrated value, and the resulting calculated value is taken as the corrected toxic equivalent C-TEQ.;COPYRIGHT: (C)2005,JPO&NCIPI
机译:要解决的问题:提供一种近似校正方法,该方法能够根据通过简便快速的测量方法获得的值来计算近似于世界卫生组织的毒性当量的校正后的毒性当量,该测量方法是使用诸如解决方案:对于采用这种测量方法的测量值,条件是要定量确定基于相应的特定反应系数的有毒化学物质(例如二恶英)与配体的每种化合物的键合量的总量确定,并且在具有共同的化学物质产生源的区域中,每种化合物的浓度组成比基本恒定,则通过使用预先获得的每种化合物的浓度组成比,估算每种化合物的估计浓度。乘以有毒的当量世界卫生组织计算综合值的系数,并将所得的计算值作为校正后的毒性当量C-TEQ .;版权所有:(C)2005,JPO&NCIPI

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