METHOD FOR DIAGNOSING CEREBRAL ACCIDENT/ASYMPTOMATIC CEREBRAL INFARCTION USING CONTENT OF POLYAMINE OR ACROLEIN, OR POLYAMINE OXIDASE ACTIVITY, OR AMOUNT OF PROTEIN OF THE OXIDASE AS INDICATOR

摘要

PROBLEM TO BE SOLVED: To provide a method for simply diagnosing a cerebral accident/asymptomatic cerebral infarction, and to provide a method for simply screening a patient suffering from the cerebral accident/asymptomatic cerebral infarction.;SOLUTION: This method for diagnosing the cerebral accident/asymptomatic cerebral infarction and the method for screening the patient suffering from the cerebral accident/asymptomatic cerebral infarction comprise each measuring an acrolein content, an polyamine content, a polyamine oxidase activity, or an amount of a polyamine oxidase protein in plasma. A possibility that the cerebral accident/asymptomatic cerebral infarction are prevented, or progress of a condition of the patient is inhibited, by inhibiting the polyamine oxidase is suggested. Further, a possibility that a remedy for the cerebral accident/asymptomatic cerebral infarction is obtained by searching a compound which inhibits the polyamine oxidase is suggested.;COPYRIGHT: (C)2006,JPO&NCIPI