CORRECTION METHOD AND DEVICE OF fMRI DATA BY OPTICAL METERING DATA

摘要

PPROBLEM TO BE SOLVED: To provide a method and a device for correcting fMRI data by optical metering data so as to be able to obtain high precision and evaluation relating to BOLD effect. PSOLUTION: A site substantially identical to a measuring site by the fMRI is irradiated with near-infrared ray, reflecting light is received, light metering obtaining a change in light absorbency of a plurality of wavelength is carried out substantially simultaneously with the measuring by the fMRI, the change of T2* signal by the fMRI is compared with the change of all hemoglobin by the light metering, and the data by the fMRI are corrected in a measurement obtaining an intrabrain blood circulation dynamic condition with a nervous activity based on the measurement of the fMRI. When data by optical metering at the time of starting the nervous activity shows the decrease of deoxidized hemoglobin it may be determined that it is not incongruent with a physical examination of BOLD effect, and when the data by the optical metering at the time of starting the nervous activity shows the decrease of the deoxidized hemoglobin and the increase of oxidized hemoglobin, it may be determined that it is not incongruent with BOLD effect to which physiologic examination is added. PCOPYRIGHT: (C)2005,JPO&NCIPI