BINAPHTHOL DERIVATIVE AND OPTICALLY ACTIVE BINAPHTHOL METAL COMPLEX CATALYST USING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide an optically active binaphthol metal complex catalyst for attaining satisfiable chemical yield and optical yield in the asymmetric nitroaldol reaction between a straight-chain aldehyde and nitromethane which has been inefficient for conventional such catalysts, and to provide a binaphthol derivative for preparing the catalyst.;SOLUTION: The binaphthol derivative is represented by general formula(1r) or (1s). An optical activator or binaphthol rare earth metal complex as the catalyst is also provided. In general formulas(1r) and (1s), R¹ is a 1-6C alkyl, 2-6C alkenyl, 7-20C aralkyl or a chain substituent containing 1-3 heteroatoms in a 1-6C alkyl group; R² is H, a halogen atom, 1-6C alkyl or 1-7C alkoxy group.;COPYRIGHT: (C)2005,JPO&NCIPI