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Its use as an agent for detecting endocrine disrupting chemicals in the environment and transgenic Xenopus embryos
Its use as an agent for detecting endocrine disrupting chemicals in the environment and transgenic Xenopus embryos
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机译:它用作检测环境和转基因非洲爪蟾胚胎中内分泌干扰物的试剂
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摘要
The invention relates to transgenic aquatic animals, particularly the clawed frog and the zebra fish and cells derived therefrom, characterized in comprising at least one expression cassette with a regulatory DNA sequence selected from the response elements to nuclear hormone receptors, particularly TRE, connected in a functional manner downstream of a DNA segment coding for a marker protein such as luciferase or GFP. The invention further relates to methods using the transgenic cells and animals according to the invention for the identification of endocrine disrupters in the environment.
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