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Nucleic acid which is expressed in hypothalamic tissue or muscle tissue of obesity animal
Nucleic acid which is expressed in hypothalamic tissue or muscle tissue of obesity animal
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机译:在肥胖动物的下丘脑组织或肌肉组织中表达的核酸
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摘要
An isolated nucleic acid molecule comprising a sequence of nucleotides encoding or complimentary to a sequence encoding a molecule or derivative or homologue thereof wherein said nucleic acid molecule is expressed in a larger amount in one or both hypothalamus tissue or muscle tissue of obese animals compared to lean animals or in fed animals compared to fasted animals. Nucleic acid sequences are disclosed. It is proposed to use the expression products of such nucleic acids as modulators and/or monitors of physiological processes associated with obesity, anorexia, weight maintenance, impaired muscle development, diabetes and/or metabolic energy levels.
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