首页> 外国专利> Method for producing a homozygous stem cell group having a genotype and immunoblotting / or types that have been selected in advance, the appropriate cell, as well as materials and methods using these transplantation of the cells derived from

Method for producing a homozygous stem cell group having a genotype and immunoblotting / or types that have been selected in advance, the appropriate cell, as well as materials and methods using these transplantation of the cells derived from

机译:产生具有基因型和免疫印迹/或预先选择的类型的纯合干细胞群的方法,合适的细胞,以及使用这些来源于细胞的移植的材料和方法

摘要

A method of producing a homogenous population of homozygous stem (HS) cells pre-selected for immunotype and/or genotype from donor cells is described herein. The invention relates to methods of using immunohistocompatible HS cells for diagnosis, therapeutic and cosmetic transplantation, and the treatment of various genetic diseases, neurodegenerative diseases, traumatic injuries and cancer. The invention further relates to methods for using histocompatible HS stem cells pre-selected for a non-disease genotype for prophylactic and therapeutic intervention including, but not limited to, therapeutic and cosmetic transplantation, and the treatment of various genetic diseases, neurodegenerative diseases, and cancer. Furthermore, the invention relates to a catalogued transplant depository of HS cells derived from multiple donors, each of the HS cells being homozygous for a unique HLA haplotype, for the purpose of having a constant, reliable, comprehensive supply of immunohistocompatible cells for diagnosis, treatment and/or transplantation.
机译:本文描述了一种从供体细胞产生针对免疫型和/或基因型预先选择的纯合干(HS)细胞的同质群体的方法。本发明涉及使用免疫组织相容性HS细胞进行诊断,治疗和美容移植以及各种遗传疾病,神经退行性疾病,创伤性损伤和癌症的治疗的方法。本发明进一步涉及使用针对非疾病基因型预先选择的组织相容性HS干细胞进行预防和治疗干预的方法,包括但不限于治疗和美容移植,以及各种遗传疾病,神经退行性疾病的治疗,以及癌症。此外,本发明涉及衍生自多个供体的HS细胞的分类移植保存物,每个HS细胞对于独特的HLA单倍型是纯合的,目的是为了提供恒定,可靠,全面的免疫组织相容性细胞用于诊断,治疗。和/或移植。

著录项

  • 公开/公告号JP2005507232A

    专利类型

  • 公开/公告日2005-03-17

    原文格式PDF

  • 申请/专利权人 ステムロン インコーポレイテッド;

    申请/专利号JP20020558483

  • 发明设计人 ヤン;ウェン リアン;

    申请日2002-01-02

  • 分类号C12N5/10;A61K35/48;A61K48/00;A61L27/00;C12N5/06;C12N15/09;

  • 国家 JP

  • 入库时间 2022-08-21 22:28:19

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号