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摘要

PROBLEM TO BE SOLVED: To provide a reagent kit capable of diagnosing active tuberculosis and syndromes caused by active MAC (Mycobacterium avium complex) disease; performing screening tests on group infection; verifying curative effects; and contributing to the diagnoses of halting of the medical treatments and to decision for discharge from hospitals, by a one-time test of simple operation and in a short time.;SOLUTION: The reagent for diagnosing active tuberculosis and active mycobacteriosis separately and independently includes, as the kit, antigens of (1) trehalose 6,6'-dimycolate (abbreviated as TDM-T) separated and purified from a M. bovis BCG Tokyo strain; (2) trehalose 6-monomycolate (abbreviated as TMM-T) separated and purified from a M. bovis BCG Tokyo strain; (3) trehalose 6-monomycolate (abbreviated as TMM-I) separated and purified from a M. avium complex (abbreviated as MAC); and (4) glycopeptide (abbreviated as GPL)-core, from which sugar chains specific to the typed of serum of a GPL antigen are removed (where the GPL antigen is prepared from phosphatidylinositol mannoside (abbreviated as PL-2) M. avium complex separated and prepared from Mycobacterium tuberculosis).;COPYRIGHT: (C)2004,JPO