Men protein, GST2, Rab-RP1, Csp, F-box protein Lilina / FBL7, ABC50, coronin, Sec61α, or VhaPPA1-1 or homologous protein involved in regulation of energy homeostasis

摘要

The present invention discloses Men protein, GST2, Rab-RP1, Csp, F-box protein Lilina/FBL7, ABC50, coronin, Sec61 alpha, or VhaPPA1-1 and homologous proteins regulating the energy homeostasis and the metabolism of triglycerides, and polynucleotides, which identify and encode the proteins disclosed in this invention. The invention also relates to the use of these sequences in the diagnosis, study, prevention, and treatment of diseases and disorders, for example, but not limited to, metabolic diseases such as obesity as well as related disorders such as eating disorder, cachexia, diabetes mellitus, hypertension, coronary heart disease, hypercholesterolemia, dyslipidemia, osteoarthritis, gallstones, cancers of the reproductive organs, and sleep apnea.