By analyzing the changes in the physiological characteristics of the network level before and after introducing the neuronal tissue sample in vitro candidate sample, the invention relates to methods and devices for the detection and characterization of psychoactive compounds. The present invention further provides a software package that allows the delivery at a particular point in the vibration-induced or spontaneous vibration, electrical pulses are timed by the operator. Temporal Such stimulation induces a useful network-level psychoactive unexpected response.
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